Our Hotel's Hospitality Makes San Pablo Feel Like Home Located near San Francisco, Berkeley, Oakland and Richmond, CA, our hotel is perfectly suited for both business and leisure travelers. Just off I-80, guests of the Holiday Inn Express® East Bay Area - San Pablo hotel can visit the major attractions and businesses of the area with ease. Corporate guests find our convenient location perfect for getting to local businesses, such as the Chevron Refinery, Doctors Medical Center, Innovex Biosciences and the Craneway Pavilion in Richmond, CA. Our hotel is only nine miles from the University of California - Berkeley. Hotel guests visiting CA are welcome to use our Business Center and 900-sq-ft conference room or executive boardroom, which are guaranteed to make your next event a success. It's not all about work here in the East Bay area. Just a short walk from our hotel's front door, San Pablo Lytton Casino offers more than 1,100 slot machines and delicious fare. We're also close to world-famous Napa Valley, Six Flags and downtown San Francisco. We love to pamper our guests from the moment they walk in the front door, so we surround them with gorgeous decor and great amenities like a sauna, Fitness Center and a complimentary, hot breakfast. Take a stroll in our garden courtyard or just relax in front of the fireplace. Book your room today to enjoy all of our hotel's perks in San Pablo!