One of the best hotels in Cayo Santa Maria, perfectly suited for your next vacation. Elegant and intimate oceanfront property offers first class dining experiences and a truly memorable and unique holiday experience. Our luxury adults-only and uses the All-In inclusive concept. All Royalton Resorts & Hotels are dedicated to providing a memorable vacation experience to enlighten, empowered and awaken your senses. Cayo Santa Maria joins your product quality, hospitality and luxury services with spirit and soul of the Cuban community. The first hotel built in the Caribbean Royalton, Royalton Cayo Santa Maria quickly became one of the best all inclusive resorts in the region. Our complex Cayo Santa Maria is located about 116 km from the International Airport of Santa Clara.