Palestine is a geographic region in Western Asia between the Mediterranean Sea and the Jordan River. It is sometimes considered to include adjoining territories. The name was used by Ancient Greek writers, and was later used for the Roman province Syria Palaestina, the Byzantine Palaestina Prima and the Umayyad and Abbasid province of Jund Filastin. The region is also known as the Land of Israel, the Holy Land, the Southern Levant, Cisjordan, and historically has been known by other names including Canaan, Southern Syria and Jerusalem.

Situated at a strategic location between Egypt, Syria and Arabia, and the birthplace of Judaism and Christianity, the region has a long and tumultuous history as a crossroads for religion, culture, commerce, and politics. The region has been controlled by numerous different peoples, including Ancient Egyptians, Canaanites, Israelites, Assyrians, Babylonians, Persians, Ancient Greeks, Romans, Byzantines, the Sunni Arab Caliphates, the Shia Fatimid Caliphate, Crusaders, Ayyubids, Mameluks, Ottomans, the British and modern Israelis and Palestinians.
Estimating the population of Palestine in antiquity relies on two methods – censuses and writings made at the times, and the scientific method based on excavations and statistical methods that consider the number of settlements at the particular age, area of each settlement, density factor for each settlement.