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Margarita Island (Isla de Margarita in Spanish) is the largest island in the Venezuelan state of Nueva Esparta, situated off the northeastern coast of the country, in the Caribbean Sea. The capital city of Nueva Esparta, La Asunción, is located on the island. Primary industries are tourism, fishing and construction.

Cities: La Asunción, Pampatar, Porlamar and Juan Griego.