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Salerno About this sound listen is a city and comune in Campania Italy and is the capital of the province of the same name. It is located on the Gulf of Salerno on the Tyrrhenian Sea. Today Salerno is an important cultural centre in Campania and Italy and has had a long and eventful history.The city is situated at the north-western end of the plain of the Sele river, at the exact beginning of the Amalfi coast. The small river Irno crosses through the central section of Salerno.