Our Florence, Alabama Hotel's Near the Tennessee River The Holiday Inn Express® Florence Northeast Hotel is located in the northwest corner of Alabama, an area best known for its variety of outdoor activities. As you visit this friendly town, pause to enjoy the surrounding countryside, which includes the beautiful Tennessee River and Pickwick Lake. Business travelers lodging in Florence appreciate our on-site Business Center and 1,008-square-foot meeting room. We are close to many major businesses, including Wise Alloys, TNT Fireworks, TVA (Tennessee Valley Authority), Coca-Cola Bottling Co., Florence Industrial Park and North American Lighting. The University of North Alabama, Eliza Coffee Memorial Hospital and Helen Keller Hospital are located in Florence, Alabama. Our hotel's property is near the Tennessee River, which boasts excellent fishing, swimming and boating. After a busy day on the river, slow down and enjoy a leisurely game of golf at The Shoals, part of the popular Robert Trent Jones Golf Trail. The family can enjoy a visit to the Alabama Music Hall of Fame, as well as the Helen Keller House and WC Handy Birthplace & Museum. You can begin each day with a fantastic meal from our complimentar, hot breakfast bar, and while lodging in Florence, our guests can also take advantage of the free high-speed, wireless Internet access we provide in each guest room. Our hotel also features an indoor pool and Fitness Center. Welcome!