Welcome to One of the Best Hotels in Salem, Virginia. Nestled in the Blue Ridge Mountains just outside of Roanoke, Virginia, the Holiday Inn Express® Hotel & Suites Salem is convenient to many surrounding businesses and attractions. For outdoor enthusiasts, this Roanoke Valley city is where you want to be. Our Salem, Virginia hotel's location is near walking and cycling paths, the Natural Bridge and Dixie Caverns, making it perfect for a nature getaway. History buffs can enjoy the historic sites peppering the surrounding area which include points of interest from the Revolutionary and Civil wars. Most hotels in Salem, VA are conveniently located near many businesses and universities, and the Holiday Inn Express® Hotel & Suites Salem is no different. Virginia Tech is 35 miles away, Radford University is 32 miles away and Roanoke College is only three miles away, making our hotel perfect for a trip to visit students or to attend special events. Business travelers appreciate our Salem, Virginia hotel's nearness to companies like General Electric, Carter Machinery and Medeco, as well as the Salem Civic Center. Our hotel's well-equipped 24-hour Business Center is also great for taking care of any last minute work. After a long day of work or play, you can relax in our outdoor pool and whirlpool spa, or work up a sweat in the 24-hour Fitness Center. We also offer a complimentary, hot breakfast bar every morning.