Welcome to the Holiday Inn Express Yreka - Shasta Area Hotel Our Yreka, California hotel is conveniently located off Interstate 5 in the northeastern corner of the picturesque Shasta Valley. Breathtaking views and historic sites abound in this Northern California city. Families can enjoy staying at our Yreka hotel while they explore everything the Shasta Valley has to offer. You can chose to stay close by and visit the Yreka Historic District with shops, restaurants, statues and museums. Then, you can learn about local history at the Siskiyou County Courthouse or take a scenic drive to Mt. Ashland, Mt. Shasta and the Klamath River. You are sure to find something you love during your Yreka vacation. Business travelers who stay at our Yreka, California hotel will have convenient access to companies such as Timber Products, Etna Breweries, Siskiyou County Offices and Siskiyou County Behavioral Health Services. Our Business Center and free high-speed, wired and wireless Internet access make our Shasta Valley hotel the perfect place for business travelers staying in the Shasta area. During your stay, enjoy a swim in the heated, indoor pool or a workout in the Fitness Center at our Holiday Inn Express Hotel in Yreka. You can start your day right every morning with the free hot breakfast bar featuring 100% Arabica Smart Roast coffee and our signature cinnamon rolls. Check out our great Yreka hotel deals, and book your stay with us today.