Welcome to the Holiday Inn Express Hotel and Suites in Greenville, AL Welcome to the newest Greenville hotel in southern Alabama. Our hotel is located right off I-65, between Mobile and Montgomery. With its southern Alabama location, our Greenville, Alabama hotel makes travel for leisure and business guests easy. Leisure travelers to southern Alabama can enjoy area attractions that are in close proximity to our hotel in Greenville, AL. If you enjoy the outdoors, you can experience Alabama's Robert Trent Jones Golf trail at Cambrian Ridge or spend an afternoon by the water at Sherling Lake. Other nearby attractions include the Hank Williams, Sr. Boyhood Home and Museum, the Greenville Historic District and the Butler County Fairgrounds. Business travelers will appreciate our Greenville, AL hotel's location, as it offers you easy access to businesses and corporations, which include Russell Stover, Hwashin, Hysco and Westpoint Steven. L.V. Stabler Memorial Hospital and the Georgiana Hospital are each within 15 miles of our smoke free hotel in Greenville, Alabama. We are proud to offer a meeting room and a business center, as well. Our Greenville, Alabama hotel offers you many amenities. You can stay connected with complimentary high-speed, wireless Internet access. Other amenities include a well-equipped fitness center, an outdoor pool and a complimentary hot breakfast. Stay Smart in the heart of Greenville, AL on your next visit.